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          Just how independent is Genentech?

          While it's not clear precisely how Roche’s Genentech division will look after its latest radical change, its makeover has been a long time coming.

          Ira mellman leaves genentech

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        5. National Academy of Sciences member Ira Mellman has presided over a small cadre of cancer biologists for nearly half a decade.
        6. Ever since Roche took full control of the business back in 2009 the Swiss company’s claim to run Genentech as an autonomous unit seemed thin, as attested to by several key executive exits.

          As such the shock departure reported on Thursday of Ira Mellman, who had served as head of Genentech’s oncology research since 2007, comes as only the latest blow.

          This move is reportedly the result of a shift that, operationally at least, will see Genentech’s oncology R&D combined into one unit, encompassing immunology and more traditional chemistry.

          Such developments are clearly disappointing, and come against the backdrop of prominent clinical setbacks at Roche in general.

          It’s not clear how the bigger structure will change; so far Roche has operated early R&D under two separate units, the Genentech-o